Evaluation of In vivo antiinflammatory activity of ethanol extract of Aristolochia bracteata retz whole plant in rats

Evaluation of In vivo antiinflammatory activity of ethanol extract of Aristolochia bracteata retz whole plant in rats

Author: 
Pious Soris Tresina, Koilpitchai Paulpriya, Vallinayagam Sornalakshmi and Veerabahu Ramasamy Mohan
Abstract: 

The present study was aimed for scientific evaluation of the antiinflammatory activity of ethanol extract of Aristolochia bracteata Retz whole plant by in vivo carrageenan induced paw edema model in albino rats. Ethanol extract showed dose dependent antiinflammatory activity. The ethanol extract has shown a significant (p< 0.001) percentage inhibition of paw edema 80.79% and 87.70% on 3 hour at 200 and 400 mg/kg respectively. The study was compared with standard drug indomethacin 85.11% (10mg/kg). This result provide a scientific basis for the use of the whole plant of A.bracteata as an antiinflammatory agent.

Paper No: 
780