Background: At the moment, people living with Human Immuno Virus (HIV) are also at increased risk of developing non communicable diseases. Antiretroviral therapy (ART) use has resulted in increasing survival and ageing among HIV-infected persons and an accompanying rise in non communicable disease co-morbidities including diabetes. Objectives: To assess the magnitude and determinants of diabetes among people living with HIV in Dessie Referral Hospital, Dessie town, North East Ethiopia, June 2017. Methods: Institutional based cross sectional study was carried for a total of 355 HIV infected individuals who were on ART selected using systematic sampling method and data were collected using exit interview from diabetes patients. Results: Out of 355 HIV infected individuals who were on ART, 6.5% had confirmed diabetes. Having sedentary work activity [AOR= 2.7, 95% CI ;( 1.1-6.3)], age greater than 35 year [AOR= 2.4, 95%CI ;( 1.3-5.94) and being overweight [AOR= 2.4, 95% CI, (1.1-6.2)] were positively associated with the development of diabetes. Conclusion and Recommendation: Generally this study shows that a significant number of HIV infected individual affected by diabetes as co morbidity. So that ART clinicians should screen ART clients for diabetes and counsel their clients for life style modifications such as regular exercise and obesity reduction.
