A study of histopathological changes in viscera in aluminium phosphide poisoning

A study of histopathological changes in viscera in aluminium phosphide poisoning

Author: 
Singh, U. R., Shailja Tiwari, Garg, S. P. and Leena Kuriakose
Abstract: 

A prospective study to observe thehistopathological findings in Aluminium PhosphidePoisoning was undertaken on 70 autopsy cases conducted at S. S. Medical College, Rewaand associated Gandhi Memorial Hospital. Aluminium Phosphide poisoning hasbecome the commonest poisoning in central India over the last few years. Aluminium Phosphide is a solid fumigant bulk grain preservative and is available in the market under various trade names like Celphos, Quickphos, Phostoxin, Phostek, Gastoxin, Zedesa, Li Fumesets. It is marketed either in Tablet or pellet form. Mortality is high as mechanism of action is not clearly understood and no specific antidote is available against this poison. Samples of tissues fromliver, lungs, kidneys and spleen were preserved in 10% Formal Saline, processed for histopathology, stained by HaematoxylinandEosin method and studied microscopically. Observations made in similar previous studies are compared with findings of present study and discussed.

Paper No: 
076