Background: In 1912 Transplant pioneer Alexis Carrell received the Nobel Prize for his work in the field. The French surgeon had developed methods for connecting blood vessels and conducted successful kidney transplants on dogs. Ukrainian doctor Yu Yu Voronoy transplanted the first human kidney, using an organ from a deceased donor. The recipient died shortly thereafter as a result of rejection (Bilgel et al., 2006). In 1982 on December 2, Barney Clark received the first artificial heart; he survived for 112 days (Taimur Saleem et al., 2009). In 2010 Spanish doctors conducted the world’s first full face transplant on a man injured in a shooting accident. A number of partial face transplants had already taken place around the world (Bilgel et al., 2006). Objectives: To assess the knowledge among undergraduate students about organ donation, their attitude and commitment towards donation of organs and various factors affecting organ donation. Methodology: A cross sectional study was planned for undergraduate students of Santhiram Medical College, Nandyal, District Kurnool, by developing a three part questionnaire in April 2014. Study was conducted and subjected for statistical analysis. Observation and Results: Study participants have heard of donation and have some knowledge of organ donation, but none have donated. No statistical association was found between age, sex, year of study, religion, socio-economic status to donate organs. Print medias were main source of information. Family person was first concern for donation. Student were reluctant to donate smokers, alcoholics addicts etc. Conclusion: Organ donation and transplantation curriculum should be included in undergraduate syallabus, looking to great need of organ donation in future.
