Hematology analysis is a swift test of blood to help monitoring health condition of fish in natural fisheries of suspected polluted rivers. To evaluate health status of fish in the White Nile River at southern Khartoum City, a total of 120 different fish species were collected from both the targeted upstream polluted area and from the non-polluted upstream area. According to routine clinical methods, the hematological parameters of PCV, Hb, WBC, RBC, MCV, MCH and MCHC were investigated. All of these parameters were found to be insignificant different (p > 0.05) comparing with control, with exception of PCV%, which found to be significantly different (p < 0.05) comparing with control in all types of fish species, as well, MCV level was found to be significantly different in Oreochromis niloticus fish species, whereas MCH was significantly different in Bagrus bayad and the MCHC test was found to be significantly different in Clarias lazera fish species. It could be concluded that, in spite of being insignificantly different comparing to control, most of these hematological analysis found to be not compliance to the suggested hematology level of healthy fish.
