Phytochemical screening, antioxidant property and anticancer potential against mcf-7 cell lines of Vernonia cinerea leaves

Phytochemical screening, antioxidant property and anticancer potential against mcf-7 cell lines of Vernonia cinerea leaves

Author: 
Varsha, V., Dr. Suresh, S. N. and Prejeena, V.
Abstract: 

To screen the phytochemicals present in petroleum ether, ethanol and aqueous extracts of leaves of Vernonia cinerea and to evaluate its antioxidant potential and anticancer activity against breast cancer cell lines. Extracts were prepared by allowing the leaf powder to react with respective solvents with continuous agitation; it is then filtered and condensed. The extracts are then screened for its phytocompounds by preliminary screening methods. Antioxidant activity was detected by DPPH, FRAP and Total Antioxidant Activity Assays Ethanol extract shown the presence of more phytochemicals. Petroleum ether, ethanol and aqueous extracts exhibited radical scavenging property at different concentrations of 10, 20, 40, 60, 80 and 100µg/mL. The extracts were tested for their anticancer potential against MCF7 breast cancer cell lines and IC50 values were calculated. Ethanol and Aqueous extracts has shown anti- cancer property. The leaves of V.cinerea thus found to possess antioxidant and anticancer properties.

Paper No: 
1214