Objectives: The rapid spread of the most virulent a novel virus SARS-CoV-2 has sparked alarm worldwide causing COVID-19, a viral respiratory disease. The World Health Organization (WHO) has declared this health-threatening outbreak as a pandemic COVID-19. In this review we diseased the COVID-19-related many questions and answers for better understanding and awareness of this disease. Study Design: Here we discussed about COVID-19, something in details as well as some more relevant associated-questions were answered from known resources. The results are shown in table format. Methods: The information and all the inputs were taken from many official organizations, like CDC, WHO, John’s Hopkins webpage, are other valuable resources. Results: Various Issues related to COVID-19, like it’s origin, severity, and symptoms. Protections and preventions, any available therapies were shown in different Tables under different headings, which are self-explanatory Conclusions: Thus the knowledge-based awareness of these recent global biological threats will be helpful to the nation-wide all people irrespective of any age, caste, religion, sex, creed, and economical status.