Purpose: To determine the relationship of collapsibility of the jugular vein as a predictor of fluid response in patients during the transoperative period at the Naval Medical Center. Methods: A cross-sectional study was conducted on 75 patients who underwent surgery at the Naval Medical Center. The internal jugular vein distensibility was measured by ultrasonography. Correlations, logistic regression analysis, ANOVA or Kruskall-Wallis and chi-square tests were used to determine differences (P ≤ 0.05) between initial compliance and final compliance during the transoperative period. Results: The distensibility of the internal jugular vein is positively related to the fluid load during the transoperative period. In the asa III and IV patients the difference was significant unlike the patients with asa I and II. Conclusions: The determination of the distensibility of the internal jugular vein in patients who will undergo surgery represents an important parameter to determine the response to fluids during the transoperative period.