This paper explores the impact of cell technology advancements on minimally invasive spondylodesis for lumbar spine degenerative-dystrophic conditions. We conducted a systematic review and meta-analysis of clinical trials from the last decade, comparing the efficacy and safety of innovative cell-based therapies with traditional surgical techniques. The focus was on stem cell applications and tissue-engineering approaches integrated into spondylodesis, aimed at enhancing osteogenesis and reducing recovery times.Data were sourced from randomized controlled trials, cohort studies, and case reports, offering a robust evaluation of the outcomes. The results indicate that cell technology significantly shortens recovery periods and increases the success rates of spinal fusions, as demonstrated by improved pain management and enhanced mobility. Furthermore, the incidence of complications like graft rejection and infections was lower in procedures augmented by cell technologies.Our findings advocate for the expanded use of cell technology in orthopedic surgery, especially for treating spinal conditions. They also highlight the need for standardized protocols and further studies to optimize these interventions and ensure sustained patient benefits. Through these technological advancements, minimally invasive spondylodesis can achieve greater effectiveness and reliability, significantly improving patient outcomes in orthopedic care.
