This study aims to compare high-school students in Turkey and the U.S., in terms of career-decision making difficulties. The research group consists of a total of 576 students, including 296 high-school students in the U.S, and 280 high-school students in Turkey. The data of the research were collected by the “Career Decision-Making Difficulties Questionnaire” (CDDQ). The career decision-making difficulties are composed of three sub-scales, including lack of readiness, lack of information and inconsistent information. Multivariate Analysis of Variance (MANOVA) was used to evaluate whether the sub-scale scores for career decision-making difficulties experienced by high-school students in the U.S. and Turkey differ depending on an individual’s gender and class. It was found that there are significant differences in gender and class variables in the career decision-making difficulties experienced by high-school students in Turkey and the U.S. The findings of the research were compared using the data collected.