Formulation and evaluation of solubility-enhanced, formalin-crosslinked sustained release lansoprazole capsule
The present study aimed to develop and evaluate sustained release formulations of Lansoprazole capsules using solid dispersion and formalin-treated gelatin capsules to enhance solubility and achieve controlled drug delivery. Preformulation studies, including organoleptic characterization, solubility testing, and FTIR analysis, confirmed the drug’s poor aqueous solubility, stability, and compatibility with selected excipients.