This research investigated the antioxidant potential of Momordica charantia (bitter gourd) in various media. The extracts have been assessed for DPPH free radical scavenging and superoxide scavenging effect. In DPPH method, IC50 values were 57. 31, 73.16, 90.52, 98.57 and 83.80 μg/ml for ethanol, aqueous, citric acid, Na2CO3 and NaCl extracts of bitter gourd respectively. In super oxide scavenging method, IC50 values of ethanol, aqueous, citric acid, Na2CO3 and NaCl were 76.09, 86.25, 99.91, 96.72 and 102.06 μg/ml respectively. The data obtained in the in-vitro models clearly establish the antioxidant potency of bitter gourd extracts with ethanol extract having the best potential and can be used in the development of medicines by isolating the active component(s).
