Biochemical changes induced by industrial effluent lead to metabolic disturbances inhibition of important enzymes, retardation of growth and reduction in the fecundity and longevity of the organism. Chronic exposure to low levels of effluent may have a more significant effect on fish populations. The acute and sub-lethal toxicity of the cement factory effluent on the fingerlings of Cirrhinus mrigala was evaluated to determine its effect on the biochemical values. The fish was exposed to varying levels of the toxicant concentrations using static bioassay to determine the median lethal concentration. The LC50 value is 1.20 per cent the fish was exposed to different hours (24, 48, 72 and 96 hours) in sub lethal concentration is 0.120 per cent. Biochemical characteristics like Protein, Carbohydrate and Lipid were estimated in gill, liver, kidney and muscle. The decrease of biochemical constituents from the control was noted. The results are statistically analysed and most of the values found to be significant.
