Mosquitoes are the most important vectors for serious human and animal diseases causing millions of deaths every year. Among these diseases, malaria, yellow fever, dengue and dengue hemorrhagic fever, filariasis and Rift Valley fever at endemic and epidemic areas in many countries. The ethanolic extract of Cleomedroserifolia was evaluated against Culexpipiens and Ochlerotatuscaspius LC50 were 178.61 & 162.63 respectively. The pupation percent was significantly reduces as a result of extract application Culexpipiens. The adult emergence was also reduced in Ochlerotatuscaspius more than Culexpipiens. The gonotrophic cycle was elongated to 8.53 and 7 for Ochlerotatuscaspius and Culexpipiens respectively. The fecundity and fertility was significantly reduced. Cleomedroserifolia extract can be used as larvicide and insect growth regulator agent in the controlling program for mosquitoes.
