To achieve the Sustainable Development Goals (SDGs), governments expect communities to participate in all development programs. In Senegal, Community-Based Organizations (CBOs) are involved in health development strategies in order to contribute locally to the achievement of Sustainable Development Goal 3 (SDG 3) dedicated to health. The aim of this study is to analyze the role of CBOs in the Diourbel commune in achieving SDG 3. A quantitative survey via a questionnaire administered to representatives of 39 CBOs followed a qualitative study via 10 individual interviews and 01 focus group of 08 targets. 39 FBOs, including 12 community watch and alert committees (CVACs), 09 health development committees (CDSs), 09 community health mutuals (MSCs) and 09 community-based organizations (CBOs) took part in the study. Respondents were predominantly male (72%), with an average age of 50. The study revealed limited knowledge and low appropriation of the SDGs and the Emerging Senegal Plan (ESP) by the CBOs. Depending on their activities, which are essentially health and socio-economic, the role of FBOs in health can be situated at three levels: prevention and health promotion, early and equitable access to quality health services, and social protection. This study shows that CBOs in the Diourbel commune play a vital role in local and sustainable health development. Their activities are perfectly in line with the targets of the national health objectives, which are aligned with those of MDG 3. However, the lack of financial resources hinders their smooth operation.