What is the underlying cause of type ii diabetes? – Are cells protecting themselves against the reactivity ofglucose?

Through the last couple of thousand years, human food sources and availability have changed tremendously. Moving from a diet of hunter gathers, consisting of nuts, fruits, tubers and meat, to the farmers’ diet of grains, milk, meat to this and last century, where among other processed foods there is the unlimited availability of refined sugar. This change in diet has been proposed as being the underlying reason for the dramatic increase in the prevalence of type II diabetes that we are observing world-wide in our time world health organization 2016. The question is what is the underlying molecular causeof this decease? One possibility proposed here is that type II diabetes might be a consequence of our cells trying to protect themselves from too high intra-cellular concentration of this reactive compound.