The oral lichenoid lesion (OLL) is response that occurs on the oral mucosa. The OLL commonly include allergic response to the dental materials, drugs, and on graft-vs-host disease (GVHD). The prevalence of oral lichen planus is more with the female predilection. Oral lichenoid lesions develop as a type IV hypersensitivity reaction. Both of those entities are potential precancerous conditions; this adds to their clinical significance. Oral lichen planus and oral lichenoid reactions are two distinct diseases. They will be clinically similar but they need different etiologic factors. A histopathological study is critical to differentiate them. The definitive diagnosis of those conditions is extremely important given their potentially premalignant nature. A timely diagnosis probably results in proper management. The aim of this study was to present a rare etiological factor the tobacco product in the incidence of oral lichenoid hypersensitive reaction.
