Medicinal plants have has a vital role in human culture and civilization. Herbal medicine as a choice for health care and the screening of medicinal plants for bioactive compounds is important. The study aimed to determine the antibacterial activity and photochemical constituents through Gas Chromatography- Mass Spectroscopy Analysis (GC-MS) and qualitative phytochemical screening of Pogostemon mollis Benth. Belongs to family Lamiaceae and also to determine the purity of crud drug by ash values. According to GC-MS analysis, totally 47 compounds were isolated by their retention indices (RI), retention time (RT) and mass spectra. The primary phytochemical analysis of the plant extracts showed the presence of various secondary metabolites like phenol, flavonoids, terpenoids, Pyosteroids, cardic glycosides, quinine and coumarians among this the methanolic plant extract showed the significant results. The ash values showed high purity of drug. A wide range of compounds were identified and they have many medicinal importances so that it can be recommended as a plant of phytopharmaceutical importance.
