Epilepsy (EP) is a ceaseless issue in modern nations because of tobacco smoking, hot food varieties, way of life changes, albuminuria, ulcers, IBS, skin rashes and deferred wounds. Many of these contemporary synthetic drugs were treated through EP-associated disease conditions to expel less therapeutic efficacy, unwanted effects and unknowing unwanted effects. Our present survey found to estimate the various parameters of antiepileptic drug-consuming patients in various zones of Kerala. The literature surveyed based on a selected cohort was used. In our study, 1500 epileptic patient details were collected and within the selection of 500 patients for the utilization of pre and post-test of drugs taken. The examination of HDL levels has shown EP and related illnesses in patients after the medications taken HDL levels for myocardial infarction (2.3 ±0.274↑) were profoundly expanded. The examination of TCH levels has plugged EP and associated diseases in patients after the medicines received TCH levels for just with EP (39.7 ± 3.613↓) and hypertension (31.9 ± 0.466↓), The examination of LDL levels have shown EP and related illnesses in patients after the medicine consuming LDL levels for hypertension (33.8 ± 3.291↓) were altogether diminished The SGOT results showed after the medications overwhelming EP+ tachyarrhythmia (2.5 ± 0.4↑) patients levels were altogether expanded. The SGPT results expressed that the medications taken EP + Inflammation (1.65 ± 0.003↓) patient's levels were wide. The WBCs enumeration levels EP and related inflammation patients after the medications taken EP (312 ±0.170↑) were increased. The assessed haemoglobin levels were unit mg/100ml of blood, which brings about the shown EP and related sicknesses Patients after the drugs received haemoglobin levels were fundamentally expanded EP (0.3 ±0.02↑) and EP + hyperlipidemic (0.2 ± 0.002↑), This utilization study ought to be a critical improvement in the more essential evaluation of destruction-relieving drug blueprints in teaching centres and all hospitals.