The present study was carried out to determine the possible bioactive components of methanolic leaf extract of Magnolia nilagirica by using GC-MS analysis. The GC-MS analysis provides different peaks determining the presence of 55 compounds were identified from the leaf extract of M. nilagirica. The main compounds in the plant extract were identified as 1Butanol, 3 – Methyl (13.25 %), 2H-Cyclohepta[b]furan-2-one (11.11 %), 5-O-Methyl-d-gluconic acid dimethylam (7.50%), Xanthanin (3.94%), 3.alpha.,6.alpha.-Dihydroxy-5.beta.-preAllopregnane-7.alpha.,11.alpha.-diol-3 (3.47%) and 2,5-Anhydro-1,6-Dideoxyhexo (3.29 %), 1,3-Cyclohexadiene (3.04%) 2,3-Dihydro-5-Hydroxy-6-Met4H-Pyran-4-one, 2,3-dihydro-3,5-dihyd (3.04%). The presence of various bioactivecompounds confirms the application of M. nilagirica for various ailments by traditional practitioners. However, the isolation of individual phytochemical constituents may proceed to find a noval drug.
