Esophageal cancer is a common cancer responsible many cancer deaths among adults worldwide. Esophageal cancer surgery is a common treatment option to improve functioning.Health related quality of life is the key functional concepts that serves to measure individuals health improvements after any treatment.This cross-sectional study was conducted at Parirenyatwa Group of hospital in Harare in Zimbabwe.Participants were selected using convenience non-probability sampling technique. A questionnaire used had 2 sections; the demographic questions and the health-related quality of life, which were adapted from the cancer-specific European Organization for Research and Treatment of Cancer of quality of life questionnaire. Data was analyzed using Statistical Package for Social sciences version 16.0. A total of 40 adults participated in this study, including 24 (60%) males and 16 (40%) females. Thirty- two (80%) of the participants had deteriorated health-related quality of life on the functions with all these participants having a mean score lower than 76, 4. Four (10%) had a stable health-related quality of life whilst 4(10%) had a much-improved health related quality of life.Health related quality of life of majority of patients could be deteriorating following surgery for esophageal cancer.
