This study was conducted to determine the Effect Of Quake Device Training On Enhancement Of Drainage In Patients With Chronic Bronchitis. Subjects: Forty patients from both sexes (22 women and 18 men )were diagnosed clinically according to GOLD 2016 have moderate (GOLD 2) COPD with age ranged from 40-60years enrolled in the study. They were chosen from outpatient clinic of chest department in Internal Affairs Police Hospitals. Methods: They were assigned into two groups equal in numbers. Group (A): Twenty patients (12 females, 8 males) received Quake device twice daily, 3time/week for 8 week plus breathing exercises (diaphragmatic and localized breathing exercises), Group (B): Twenty patients received (10 females, 10 males) received postural drainage twice daily that was carried out according to sputum anatomical presentation revealed in the chest radiograph (x- ray)., 3time/week for 8 week plus breathing exercises (diaphragmatic and localized breathing exercises). They were assessed by taking blood samples to measure arterial blood gases (Pao2, Paco2, pH, Hco3) using arterial blood gases analyzer. Results: There was significant difference when comparing between pre and post-treatment mean values of the measured arterial blood gases as for group A it showed percentage of improvement in Pao2(mmHg) (23.27%), Paco2 (mmHg) (12.89%),pH( 3.87% ) and Hco3 (mmHg)(35.3%) improvement while group B The results showed a much lesser improvement asPao2(mmHg) (14.25%), Paco2 (mmHg)(6.18%), [H (mmHg) (2.4%) and forHco3 (mmHg) (16.74%).Conclusion: It was concluded that management of removing secretions with quake and posture drainage is likewise important by both methods with furthermore noticeable enhancement in quake training than in posture drainage.