Por qué perfusiones controladas por objetivo en neurocirugía?: cambiando paradigmas
Introduction: The objectives of neuroanesthesic management should focus on generating unconsciousness, amnesia and antinociception, maintaining cerebral perfusion pressure, control of intracranial pressure, avoiding secondary damage due to hypoxemia, hypo or hypercapnia, hyper or hypoglycemia, to thus being able to provide optimal surgical conditions, allowing in turn early neurological evaluation. Objectives: The present review aims to evaluate in a practical way the main pharmacokinetic models and correlate them with the changes that occur in neurosurgical patients.