Health Sciences

A study of serum lipid profile in chronic liver diseases

Background: Liver is the main site for the metabolism of lipoproteins, fatty acids and cholesterol. Liver diseases can affect plasma lipid levels in a variety of ways. Chronic liver diseases due to various causes are often associated with dramatic reductions in plasma triglyceride and cholesterol level due to reduced lipoprotein biosynthetic capacity. The study was conducted to determine the lipid profiles in patients with chronic liver disease and to determine if it correlates with the severity of the chronic liver disease.

Health related quality of life among adults after surgery for esophageal cancer: a cross sectional study in harare, zimbabwe

Esophageal cancer is a common cancer responsible many cancer deaths among adults worldwide. Esophageal cancer surgery is a common treatment option to improve functioning.Health related quality of life is the key functional concepts that serves to measure individuals health improvements after any treatment.This cross-sectional study was conducted at Parirenyatwa Group of hospital in Harare in Zimbabwe.Participants were selected using convenience non-probability sampling technique.

A review of the complex humanitarian emergency in the boko haram embattled region of northeastern nigeria: a call for global partnership by aid organizations

Complex Humanitarian Emergencies (CHE’s) result in widespread displacement of communities, with attendant public health consequences. CHE’s constitute a huge burden in the fight against the spread and eradication of several communicable diseases. When CHE’s occur, they result in the loss of lives, and impose strains on health systems. Unfortunately, the victims of this catastrophic situation may have limited access to primary healthcare services. To compound the problem, donor aid may become limited, due to security concerns and the ensuring instabilities in the region.

Evaluation of zinc deficiency and its associated factors among pregnant women attending antenatal care at the sub district hospital chimur, chandrapur, maharashtra, india

Background: Zinc deficiency during pregnancy has far-reaching consequences on both mother and fetus and subsequent child survival. However, data on the prevalence and determinants of zinc deficiency among pregnant women are scanty and inconclusive. The aim of this study was to assess the prevalence of zinc deficiency and associated factors among pregnant women attending antenatal care at the Sub District Hospital Chimur, Distrct Chandrapur, Maharashtra, India. Methods: Institution based cross-sectional study was conducted at the SDH Chimur from July 2015 to April 16.

Evaluation of tuberculosis in hiv patients using the xpert mtb/rif assay and its rifampicin resistance pattern at tertiary care center in north india

Background: Tuberculosis (TB) is the most common opportunistic infection among people living with HIV. It is also the leading cause of death among people living with HIV. Patients with HIV-pulmonary tuberculosis co-infection are most likely benefitted by Xpert MTB/RIF Assay. Aims & objective: Evaluation of Tuberculosis in HIV patients using the Xpert MTB/RIF assay and its rifampicin resistance pattern at tertiary care center in north India.

A pulmonary aspergillus niger infection in a diabetic ketoacidosis patient

Pneumonia is the most common reason for diabetic ketoacidosis. Although the pathogen was uncommonly Aspergillus niger. Aspergillosis is opportunistically found in human individuals. The onset was insidious but the disease progressed quite rapidly. Herein we have reported a case of diabetic ketoacidosis that was associated with invasive pulmonary Aspergillus niger infection After receiving Fluconazole and amphotericin B, the patient recovered gradually three months later.

Ectopic kinetoplast in trypanosomes of wild clarias gariepinus from sokoto and zamfara states, nigeria

Members of the Trypanosomatidae family responsible for sleeping sickness in man and debilitating disease in animals share common feature of structural organelle arrangement with other eukaryotes. While screening blood of four species of wild fish of Northern Nigeria (Clarias gariepinus, Mormyrus rume, Bagras bayad, and Tilapia zilli) from 2 locations in Sokoto and Zamfara States for trypanosomes, two unfamiliar morphotypes of bloodstream trypamastigotes were incidentally observed in two Clarias gariepinus from Rabah and Nato dams respectively.

Preformulation parameters of formulation and development of new dosage form

This review article focus on the various preformulation parameters which effect the development of new dosage form like drug solubility, dissolution rate, partition coefficient, polymorphic forms and stability. Every drug has intrinsic physical and chemical properties which have been consider before development of pharmaceutical formulation. This property provides the framework for drug’s combination with pharmaceutical ingredients. Preformulation studies carried out by various researchers and scientists are reviewed.

The effect of medication reviews on reducing medication anticholinergic burden in elderly patients

Anticholinergic side effects of medications often misdiagnosed as cognitive function decline in the elderly. The study aims to explore the effectiveness of home medication reviews on reducing anticholinergic burden caused by medications with anticholinergic properties in elderly patients in Australia. The study was a qualitative, prospective, observational case-control study. Interviews at baseline and six-month were performed. Medications changes were theoretically possible to reduce the Anticholinergic Cognitive Burden score, but occasionally are impractical to implement.

Study on perception and attitude of mothers regarding pentavalent vaccine in dist bathinda, Punjab

Immunization is one of the most important public health interventions and a cost effective strategy to control the infectious diseases especially in children. Advent of combination vaccines has facilitated incorporation of additional vaccines into immunization schedule. Pentavalent vaccine, against five killer diseases–diphtheria, pertussis, tetanus, hepatitis B and Hemophilus influenza type B (Hib), has been introduced in almost all GAVI eligible countries by 2011 and it was launched in Punjab on 7thjan 2015.