The study examined pain reduction level of patients with knee osteoarthritis after a 12-weekexercise programme: Coronavirus prevention protocols implication. Lack of physical activity is associated with muscle weakness, pain, joint stiffness, decreased range of motion and general deconditioning which lowers immunity. The research design is quasi- experimental. Sample consist of randomly selected 100 knee osteoarthritis patients, age range of 25-85 years, clinically diagnosed with mild to moderate knee deformity, without record of knee surgery. Height, weight, BMI were recorded.