Health Sciences

Acute and subacute toxicity study of water extract of leaves of guiera senegalensis j.f.gmel (combretaceae) in wistar rats

The plant was investigated for possible toxicity (both acute and subacute toxicity) in wistar rats. Twenty five female rats were divided into five groups of five rats each. The first group was orally dosed with 2000 mg/kg body weight of the extract for acute toxicity testing. The remaining four groups were used for subacute testing and were dosed as follows; group A received orally administered distilled water, group B received 50mg/kg, and groups C and D received 100 and 200 mg/kg respectively of the extract orally.

The impact of specialtyon the knowledge of physical activity and sports of varna medical college students

Physical activity is a substantial factor for mental and physical development of each person. The optimal physical activity plays an importantrole in the prevention of socially significant diseases. The aim of this article is to study the impact of specialty on the knowledge of physicalactivity and sports among students from two specialties from the Medical College of Varna. The study includes 76 students from Varna Medical College from the following specialties “Inspector of Public Health” (IPH) and “Rehabilitator”.

Hereditary spherocytosis and gallstones formation

Hereditary spherocytosis (HS) is a heterogeneous group of hemolytic anemia caused by deficiency or dysfunction of red blood cell (RBC) cytoskeletal proteins. It is a common disorder located mostly in Caucasian population; most affected individuals have mild or only moderate hemolysis. In a few rare cases, the measurement of RBC membrane proteins is required to clarify the nature of the membrane disorder in absence of the family history. Patients with HS are at more risk of developing gallstones, whose prevention represents a major impetus for splenectomy in such patients.

Family caregiver burden the patient with diabetic foot in the navy specialty hospital of veracruz

OBJETIVE: Determinate the family burden in the caregiver of the patient with diabetic foot in the Naval Specialty Hospital of Veracruz. METHODS: The caregiver of a patient with a diabetic foot was observed attending to the wound clinic, monthly period of June to October 2016. The Self-Applied Family Load Scale-Questionnaire was applied to him, through three sections, the objective load, the level of attribution and the subjective load with a reliability of 0.85 No-random sampling and probabilistic sample.

Risk factors associated with the most frequent complications in diverticular disease after its surgical resolution at the naval general hospital of high specialty

Introduction: Complications due to Diverticular Disease (ED) have a prevalence of 25%. Its clinical presentation may be in abscesses, stenosis, fistulas, bleeding and perforation that will merit urgent or elective surgical treatment. The risk factors associated before and after surgical resolution have not yet been well determined. Objective: To identify the risk factors associated with the most frequent complications of ED that occur in patients of the Hospital General de Naval de Alta Especialidad (HOSGENAES) and the type of surgical treatment most used for resolution.

Effectiveness of test of tromboelastografia against global coagulation tests as a guide in treatment of patients with chronic hepatic or renal insufiencia showing an episode of "hemorrhage"

Background: Mortality from hemorrhage in renal failure and liver, chronic units critical is 40% and the deleterious effects related to transfusion are high, the decision to transfuse should be selected, methods of interpretation of coagulation go global test methods like tromboelastograma, however what is most effective for guiding a better decision making?

Halting of functional decline in a case of duchenne muscular dystrophy after cellular therapy

Duchenne muscular dystrophy (DMD) is an X-linked genetic myopathy characterized by progressive skeletal muscle degeneration and weakness. Recent studies have shown that stem cell derived exosomes promote angiogenic and cardioprotective function of cellular therapy. With no known cure, cellular therapy has shown some promise in altering the disease process. We report a case of DMD treated with autologous bone marrow mononuclear cell (BMMNC) transplantation followed by long term multidisciplinary rehabilitation.

Use of near infrared spectroscopy monitor and its relationship in the early detection of postoperative delirium in elective surgeries of geriatric patients in hosgenaes

Introduction: Postoperative delirium is a complication that frequently occurs in post-operative patients, both in cardiac and non-cardiac surgery, with the most affected being the elderly. Diagnostic criteria for delirium or cognitive impairment are documented in the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). The incidence reported on this entity varies between 25-80%, and its diagnosis will depend on its definitions, forms of presentation, type of surgery and time of its evaluation in the postoperative period.

MDR1 mRNA Expression by real time - pcr and relationship with clinical response before and after giving neoadjuvant chemotherapy regimen cyclophosphamid-doxorubicin-5fu cdf) in local advanced breast cancer labc)

Background: Chemoresistanceinvolving P-gp / MDR1 as uncertain factors affect the clinical response after the administration of neoadjuvant chemotherapy NAC) regimen Cyclophosphamid-Doxorubicin-5FU CDF). Response to chemotherapy can be assessed by changes in mRNA expression of MDR1 gene due to DNA damage in the cancer cell DNA synthesis by examination of quantitative Real Time PCR qRT-PCR). Objective: Knowing the direction of change in MDR1 mRNA expression before and after administration of NAC regimen CDF on Local advanced breast cancer LABC) based clinical response.