Triple-negative breast cancer: Therapeutic strategies
Triple-negative breast cancer (sometimes abbreviated TNBC) refers to any breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu, detected in 8-20% of cases, the most aggressive with a poor prognosis.. Breast cancer (BC) is the most frequent tumor worldwide. In 2016, 1,380,000 new cases and 458,000 deaths for BC were reported worldwide, of which there were 332,000 new cases and 79,000 deaths in Asia.