Health Sciences

Triple-negative breast cancer: Therapeutic strategies

Triple-negative breast cancer (sometimes abbreviated TNBC) refers to any breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu, detected in 8-20% of cases, the most aggressive with a poor prognosis.. Breast cancer (BC) is the most frequent tumor worldwide. In 2016, 1,380,000 new cases and 458,000 deaths for BC were reported worldwide, of which there were 332,000 new cases and 79,000 deaths in Asia.

A study for evaluation of clinical outcome of endoscopic sinus surgery in patients of chronic rhinosinusitis

Chronic rhinosinusitis (CRS) is an inflammatory condition of nasal and paranasal mucosa. It has both medical and surgical modalities of treatment. The evaluation of clinical profile of a patient can be done both subjectively using SNOT 20 scoring and objectively using Lund and Mackey endoscopic scoring and NCCT for imaging for assessment of efficacy of the treatment modality. The most effective modality of treatment of CRS has always been a debate amongst surgeons both in respect to modality as well as timing and type of surgical intervention.

Correlation of vitamin d level with body mass index and waist circumference in diabetic population

Objecive: The objective of the study to investigate the correlation of vitamin D level with body mass index and waist circumference in diabetic population. Patients and Methods: An observational cross-sectional study on 100 subjects (male=55 and female=45), age range 30-60 year, was performed. Subjects underwent physical examination and biochemical testing. Subjects included were newly diagnosed or previously diagnosed case of diabetes mellitus. Analysis was performed using SPSS Statistical package for windows (SPSS VERSION 20).

Inguinal hernia in pediatrics, comparison of results of open surgery and laparoscopic

Introduction: Inguinal hernia in children can threaten life or cause loss of organs. It requires an elective surgical approach, through open surgery or laparoscopic. Objective: To compare the results of laparoscopic surgery versus open technique in indirect inguinal hernia in pediatric patients operated on in the General Hospital High Specialty Naval.

Prevalence of kidney disease in apparently healthy children with risk factors of high specialty naval general hospital

Background: there is little information about the prevalence of kidney disease in early stages, especially focused on pediatric age, this is because the disease is asymptomatic during these stages, a timely diagnosis with strict follow up Objective: to know the prevalence of kidney disease in apparently healthy children with risk factors.

Platelet mapping in patients with hip fracture and chronic ingestion of antiaggregants that require surgical treatment

Background: There are currently a large number of elderly patients with hip fracture who require surgical treatment; However, it can be delayed by the intake of antiaggregants, which justifies the present study to avoid delaying the definitive treatment and thus reduce the associated morbidity and mortality. Objective: To establish the behavior of platelet mapping in patients with chronic intake of antiaggregants that have required surgical treatment for hip fracture. Methods: 51 patients were included in the HOSGEAES from 2015 to 2016. They were divided into three groups: A.

Correlation of the inferior vena cava index and hemodynamic stability in the transoperative period in the high specialty naval general hospital

Background: Fluid management in anesthesiology during the transanesthetic period is of vital importance. It represents a challenge for the anesthesiologist, especially in patients who are not hemodynamically stable. Objective: To report the correlation between the vena cava collapsibility index and the hemodynamic stability of patients under general anesthesia during the transoperative period Methods: The data were coded and stored in the Microsoft Excel software and analyzed using the SPSS version 17 software. The statistical significance was defined as a P value <0.05.

“Dental” health economics of rural India

Health and healthcare require particular attention from economists in order to consider the use of resources devoted to producing healthcare and improving oral health. Health economics is the application of the principles of economics to healthcare sector. The extensive rural population and school children are denied of even the basic dental services though there is continuous advancement in the field of dentistry. The various studies have revealed an increasing trend in oral diseases in the recent times especially among this underserved population.

Conjunctival myxoma in a pediatric patient: A case report

Conjunctival Myxomais a rare benign neoplasm, with a Mesenchymal origin. We emphasize the importance of excisionalbiopsies to diagnoseindeterminateconjunctivallesions. The patient present schemos is and translucentconjunctival mass in therighteye, he under went a next ensive evaluation as well as multidisciplinary management, with out evidence of systemicdiseaseassociated with Conjunctival Myxoma was found. The complete excision of the tumor is the optimal treatment as itcontributes to the his to pathological examination for confirmation.

Low lymphocyte-to-monocyte ratio is associated with an enhanced regulatory t lymphocyte function in metastatic cancer patients

Despite their different mechanism of action, the antitumor efficacy of overall anticancer therapies would depend not only on their antitumor cytotoxic activity, but also on the immune biological response of cancer patients, which is the result of interactions between immunostimulatory and immunosuppressive events. Today, it is known that the anticancer immunity is mainly depending on T helper (TH) (CD4+) and dendritic cells, whereas it inhibited by the macrophage system and regulatory T lymphocytes (T reg) (CD4+CD25+).

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